Withdrawal
Kratom Withdrawal: Symptoms, Timeline, and What to Expect
Medically Reviewed By
Written By
Last medically reviewed July 21, 2025
Withdrawal
Medically Reviewed By
Written By
Last medically reviewed July 21, 2025
Kratom withdrawal can hit hard, both physically and emotionally. Some people feel achy and unwell, as if they’re coming down with the flu. Others struggle with side effects like anxiety, low mood, or restlessness that won’t go away. [1]
Withdrawal syndrome symptoms can start quickly and manifest in various ways for different individuals.
While it’s not easy, it is temporary, and there are ways to get through it and start feeling better.
Kratom (Mitragyna speciosa or mitragynine) is derived from leaves of a tropical tree native to Southeast Asia. It’s often used for chronic pain relief or as an energy booster, according to the National Institute on Drug Abuse. [2]
Inside the body, it works a lot like opioids despite not being a controlled substance as defined by the Drug Enforcement Administration (DEA). [3]
Kratom binds to opioid receptors in the brain—the same ones that respond to drugs like morphine or heroin. Over time, this can lead to kratom addiction and dependence, even if it started as casual use.
When you take kratom often, your brain and body start to rely on it to feel balanced. If you suddenly stop following kratom dependence, your system doesn’t know how to respond right away. [4] That’s when withdrawal kicks in for kratom users.
Your body has to adjust to functioning without kratom, which can cause both physical and emotional symptoms that may require medical attention and healthcare.
When someone stops using kratom, the body and brain can react in several ways. These withdrawal symptoms are often uncomfortable but usually not life-threatening.
They can affect both your physical health and your emotional well-being. Here’s what to expect.
Many people describe the physical side effects of kratom withdrawal as flu-like. [5] These symptoms may start within hours of the last dose and can include:
Kratom doesn’t just affect the body—it has a real impact on how you think and feel. [6] Once you stop using it, your emotions can swing in ways that feel hard to control.
These mental and emotional symptoms are a normal part of withdrawal stemming from physical dependence, but they can be frustrating and draining. Having support makes a big difference.
Kratom withdrawal usually starts quickly and can last for several days. For some people, symptoms go away within a week.
However, others may experience post-acute symptoms that persist for a longer period. The timeline depends on how much kratom you’ve been using, how often, and for how long. [7]
Acute withdrawal symptoms typically start within 6 to 12 hours after the last use of kratom. [8] They usually get worse over the first few days:
During this time, people may feel physically sick and emotionally overwhelmed. It can feel a lot like having the flu, but with added anxiety and cravings.
After the initial withdrawal ends, some people go through post-acute withdrawal. This phase can last weeks or even months, especially for long-term or heavy users.
Common post-acute symptoms include:
These symptoms often show up in waves. You might feel fine for a few days, then suddenly feel off again. That’s part of the post-acute cycle—and it’s normal following drug addiction and dependence.
Stage | Timeframe | Common Symptoms |
Acute Withdrawal | Days 1–7 | Sweating, nausea, insomnia, anxiety, runny nose, changes in blood pressure |
Post-Acute Withdrawal | Weeks to months | Cravings, depression, low energy, poor focus |
Kratom withdrawal symptoms can range from uncomfortable to overwhelming. Certain factors can make the process harder, both physically and emotionally, including: [9]
Many people turn to kratom because they believe it’s a “natural” or safer alternative to opiates or opioids—but that doesn’t mean withdrawal is easy. In fact, the symptoms of kratom withdrawal can be surprisingly similar to those seen with opioid addiction.
Understanding how kratom withdrawal compares to opioid withdrawal helps people take it seriously.
Even though kratom is legal in many places and marketed as a “natural” supplement, it can still lead to drug dependence and a difficult detox process, as is true with other forms of substance abuse.
Knowing what to expect—and how it compares to other substances—can help individuals make informed decisions about their health and recovery.
There’s no one-size-fits-all way to quit kratom, but safety and support can make a big difference in how manageable the process feels.
Some people try to quit on their own at home, but this can come with challenges:
Supervised detox isn’t just about comfort—it’s about safety and support, especially if mental health concerns or past trauma are involved.
Whether in outpatient or residential settings, treatment programs can offer tools that help people get through withdrawal and stay off kratom long-term. These may include:
The right combination of support can make withdrawal feel less overwhelming—and help set the stage for lasting change.
Kratom withdrawal can be tough, but it doesn’t last forever. The symptoms may feel intense in the moment, but they fade with time, and there are ways to make the process easier.
If you’re feeling overwhelmed, it’s okay to reach out. You or your loved one doesn’t have to do this alone. With the right support, recovery is possible—and it’s worth every step.
Most people begin to feel symptoms within 12 hours of their last dose. Early signs include restlessness, body aches, irritability, and anxiety. [11]
Kratom withdrawal is usually not life-threatening, but it can be physically and emotionally intense. [12] Those who have underlying mental health issues or a history of heavy use may face more severe symptoms.
Post-acute symptoms—like low mood, cravings, and brain fog—can last for several weeks or even months. These symptoms often come in waves but gradually fade over time.
While there’s no medication made specifically for kratom withdrawal, a healthcare provider may use other non-opioid medications to help with symptoms like anxiety, nausea, and sleep issues.
Some people are able to quit on their own or follow a tapering plan, especially with mild use. For others, especially those with heavy or long-term use, medical support can make withdrawal safer and less overwhelming. Professional addiction treatment may be needed in some cases as well.
[1] Smith, K. E., Dunn, K. E., Rogers, J. M., Garcia-Romeu, A., Strickland, J. C., & Epstein, D. H. (2022). Assessment of Kratom use disorder and withdrawal among an online convenience sample of US adults. Journal of Addiction Medicine, 16(6), 666–670. https://pure.johnshopkins.edu/en/publications/assessment-of-kratom-use-disorder-and-withdrawal-among-an-online-
[2] [10] Kratom. (2022, March 25). National Institute on Drug Abuse. https://nida.nih.gov/research-topics/kratom
[3] DEA. (n.d.). Kratom. https://www.dea.gov/sites/default/files/2020-06/Kratom-2020_0.pdf
[4] Abdullah, M. F. I. L. B. (2020). Kratom Dependence and Treatment Options: A Comprehensive Review of the Literature. Current Drug Targets, 21(15), 1566–1579. https://pubmed.ncbi.nlm.nih.gov/32682371
[5] [6] Singh, D., Müller, C. P., & Vicknasingam, B. K. (2014). Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users. Drug and Alcohol Dependence, 139, 132–137. https://pubmed.ncbi.nlm.nih.gov/24698080/
[7] What data exists on the use of buprenorphine and buprenorphine-naloxone for the treatment of kratom withdrawal? | Drug Information Group | University of Illinois, Chicago. (n.d.). https://dig.pharmacy.uic.edu/faqs/2023-2/august-2023-faqs/what-data-exists-on-the-use-of-buprenorphine-and-buprenorphine-naloxone-for-the-treatment-of-kratom-withdrawal/
[8] [9] [11] [12] Henningfield, J. E., Chawarski, M. C., Garcia-Romeu, A., Grundmann, O., Harun, N., Hassan, Z., McCurdy, C. R., McMahon, L. R., Sharma, A., Shoaib, M., Singh, D., Smith, K. E., Swogger, M. T., Vicknasingam, B., Walsh, Z., Wang, D. W., & Huestis, M. A. (2023). Kratom withdrawal: Discussions and conclusions of a scientific expert forum. Drug and Alcohol Dependence Reports, 7, 100142. https://pmc.ncbi.nlm.nih.gov/articles/PMC10311168/