Substances
Does Adderall Raise Your Blood Pressure Long-Term?
Medically Reviewed By
Written By
Last medically reviewed June 16, 2025
Substances
Medically Reviewed By
Written By
Last medically reviewed June 16, 2025
Adderall XR (extended release) can lead to various short-term and long-term health effects. When taken as directed, these effects tend to be minimal.[1] However, using excessive doses significantly raises the risk of negative side effects, including dangerously elevated blood pressure.[2] Due to the increased blood pressure risk, individuals with certain heart-related conditions may want to avoid taking Adderall.
This guide outlines how Adderall works, specifies individuals who should avoid it, and examines its impact on blood pressure.
Adderall is a prescription stimulant primarily prescribed to individuals with attention-deficit hyperactivity disorder (ADHD).[3] However, individuals with the sleep disorder narcolepsy can also benefit from its use.
This medication is made from a combination of two stimulants: amphetamine and dextroamphetamine.[3] These stimulants affect chemicals in the central nervous system that contribute to hyperactivity and impulsivity.
Adderall is a lifesaver for individuals with uncontrolled attention-deficit hyperactivity disorder. It provides essential relief, allowing them to focus on tasks for longer periods while decreasing their impulsivity and hyperactivity. Without appropriate treatment, many of these individuals face challenges in their academic and professional lives and find it difficult to maintain healthy relationships due to their impulsive and inattentive tendencies.
Individuals with ADHD experience lower dopamine levels than the average person.[4] This neurotransmitter is typically released during rewarding activities, providing a sense of exhilaration. However, those with ADHD do not experience this rush, leading them to continually pursue it.
Adderall works by increasing levels of three feel-good hormones: dopamine, norepinephrine, and serotonin.[5] This takes the user’s brain from a state of agitation and disarray to a normal state of stimulation.
There are several side effects associated with taking the prescription drug Adderall.[6]
Common side effects include:
Other potential side effects include:
Less common side effects include:
Rare but serious side effects include:
Many of the side effects will dissipate gradually after discontinuing Adderall use. However, a number of long-term side effects are associated with its misuse.
They include:[7]
According to the National Institute of Health, stimulants increase respiration, heart rate, and blood pressure.[8] However, this rise in blood pressure is not significant enough to justify the use of high blood pressure medication.
Individuals with normal blood pressure will not develop high blood pressure from taking Adderall, although they may test on the higher side of normal. Individuals with pre-existing hypertension may need medication to treat their high blood pressure before taking Adderall.
Note: This medication may not be suitable for individuals with uncontrolled hypertension. Hypertension is defined as a systolic pressure exceeding 130 and a diastolic pressure exceeding 80.[9]
Adderall constricts blood vessels, leading to higher-than-usual blood pressure.[10] This can exacerbate existing hypertension, increasing the risk of cardiovascular events. Therefore, some individuals with high blood pressure shouldn’t take Adderall. If you have hypertension or a pre-existing heart condition, it may be best to use a non-stimulant treatment for ADHD, such as Strattera or Intuniv.[11]
If you currently have high blood pressure and experience any of the following symptoms while taking Adderall, contact your physician right away:[6]
Note: It’s important to keep track of your blood pressure while on Adderall, especially those who have a previous diagnosis of hypertension.
If you are currently taking Adderall, it is important to consult your physician before stopping your prescription. Sudden discontinuation can result in serious withdrawal symptoms.[12] Instead, work with your physician to gradually taper your doses or consider switching to another medication.
If you are taking more Adderall than prescribed, despite it causing health concerns, you may have an addiction.
Signs of Adderall addiction include:[13]
If you’ve experienced any of the above signs, it’s essential to work with someone to help you overcome your addiction. Continuing to abuse stimulant drugs like Adderall can lead to permanent health complications and an increased risk of bodily injury.[14]
At Southeast Addiction Center GA, we are dedicated to supporting you on your healing journey. We offer a variety of science-backed treatment programs designed to help you uncover the root causes of your addiction and identify your triggers. Our evidence-based methods are focused on empowering you to overcome these challenges.
No matter where you are in your recovery, we are here to assist you every step of the way. Remember, there is hope and help available for your recovery.
Contact us today for a no-obligation consultation with one of our caring specialists. Remember, you don’t have to fight Adderall addiction alone. Let us work together to help you reclaim the life you deserve.
Adderall is a stimulant medication used for the treatment of narcolepsy and ADHD. It is formulated from two chemical stimulants, dextroamphetamine and amphetamine. It is available by prescription only and is listed as a controlled substance.
Stimulant medication, such as Adderall, constricts blood vessels in the body, increasing respiration, heart rate, and blood pressure. It is common to have a higher-than-usual blood pressure reading while taking prescription Adderall. However, if the reading exceeds your normal, contact your physician.
No, the increased blood pressure effect of Adderall is only present until the medication is fully eliminated from your body. After this, your blood pressure should return to normal. Should your blood pressure remain high after this time, it is best to get it evaluated by a medical professional.
Individuals with uncontrolled high blood pressure should avoid taking Adderall, as the risks may outweigh the benefits. However, if you are currently taking medication to control your blood pressure and your physician has prescribed Adderall, they have determined that the benefits outweigh the risks.
Medications such as clonidine and Hyzaar are very common and can be used while taking Adderall, though not at the same time. Speak to your pharmacist about the best way to space these medications out for maximum effectiveness.
Until there are complications, most people with high blood pressure are unaware that they have it. This is why the American Heart Association considers hypertension the silent killer. The only way to know you have high blood pressure is to take a blood pressure reading regularly. You may use a portable blood pressure monitor in a physician’s office or at home.
A systolic reading of 130 or higher or a diastolic reading of 80 or higher is considered stage one hypertensive. While it is common to have a reading this high after extreme activities, it is not common to have a reading this high when resting.
[1] National Library of Medicine. (2008 Aug 8). Potential Adverse Effects of Amphetamine Treatment on Brain and Behavior: A Review. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC2670101/ on 2025 May 12.
[2] Stat Pearls. (2024 May 6). Amphetamine Toxicity. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK470276/ on 2025 May 12.
[3] Vital Record. (2015 Sep 22). You Asked: What Does Adderall Do To Your Body? Retrieved from https://vitalrecord.tamu.edu/you-asked-what-does-adderall-do-to-your-body/ on 2025 May 12.
[4] Attention Deficit Disorder Association. (n.d.)How Dopamine Influences ADHD Symptoms and Treatment. Retrieved from https://add.org/adhd-dopamine/ on 2025 May 12.
[5] Stat Pearls. (2023 July 31). Amphetamine. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK556103/ on 2025 May 12.
[6] Drugs.com. (2024 Aug 8). Adderall Side Effects. Retrieved from https://www.drugs.com/sfx/adderall-side-effects.html on 2025 May 12.
[7] U.S. Food and Drug Administration. (2007 Mar). Adderall CII. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011522s040lbl.pdf?utm_source=content&utm_medium=article&utm_campaign=ozempic_muscle&utm_id=%20ozempic_muscle on 2025 Mar 12.
[8] National Library of Medicine. (2025 Mar 28). Effect of Amphetamine on Blood Pressure. Retrieved from https://pubmed.ncbi.nlm.nih.gov/40152309/ on 2025 May 13.
[9] American Heart Association. (2024) What is High Blood Pressure? Retrieved from https://www.heart.org/-/media/files/health-topics/answers-by-heart/what-is-high-blood-pressure.pdf on 2025 May 13.
[10] Library of the U.S. Court of the Seventh Circuit. (2020 Apr 16). Effects of Adderall on the Body. Retrieved from https://www.lb7.uscourts.gov/documents/19-824URL1TheEffectsofAdderallonYourBody.pdf on 2025 May 13.
[11] Drugs.com (2024 Aug 19). Strattera and Adderall: What’s the Difference? Retrieved from https://www.drugs.com/medical-answers/strattera-adderall-difference-3121641/ on 2025 May 13.
[12] Drugs.com. (2024 Apr 9). How Long Does Adderall Withdrawal Last? Retrieved from https://www.drugs.com/medical-answers/long-adderall-withdrawal-3572393/ on 2025 May 13.
[13] American Psychiatric Association. (2024 Apr). What is a Substance Use Disorder? Retrieved from https://www.psychiatry.org/patients-families/addiction-substance-use-disorders/what-is-a-substance-use-disorder on 2025 May 13.
[14] U.S. Food and Drug Administration. (2023 Oct). Adderall CII. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/011522s045lbl.pdf on 2025 May 13.